433 Marlborough was built in 1885 for Chadwick & Stillings, for speculative sale, one of eight contiguous houses (431-445 Marlborough). Chadwick & Stillings (N. Henry Chadwick and Oscar L. Stillings) was a hat block and flange company that became a significant house building firm in the 1880s and 1890s. They are shown as the owners, architects, and builders on the original building permit application for 433 Marlborough, dated June 16, 1885.
By the 1886-1887 winter season, 433 Marlborough was the home of Dr. Edward C. Briggs and his wife, Lou (Lord) Briggs. They previously had lived at 5 Walnut. He is shown as the owner of 433 Marlborough on the 1888 Bromley map.
Edward Briggs a physician and dentist, and a professor at Harvard Medical School. He maintained his office at 1 Mt. Vernon.
By the 1888-1889 winter season, Edward and Lou Briggs had moved to the Hotel Brunswick (southeast corner of Clarendon and Boylston). At about the same time, he purchased 125 Marlborough, which he converted into medical offices and residential units. When the remodeling was completed, he moved his office there.
By the 1888-1889 winter season, 433 Marlborough was the home of Joaquin Job Souther and his wife, Gertrude Mae (Bouvé) Souther. They had married in August of 1888 and 433 Marlborough probably was their first home together. Joaquin J. Souther is shown as the owner of 433 Marlborough on the 1895 and 1898 Bromley maps.
Joaquin Souther was a brewer in his father’s firm, Joaquin K. Souther & Son, operators of the Burton Brewery, makers of ale and porter.
The Southers continued to live at 433 Marlborough during the 1908-1909 winter season, after which they made their home in Hingham.
Charles R. Ball et al, trustees, are shown as the owners of 433 Marlborough on the 1908 Bromley map.
By the 1909-1910 winter season, 433 Marlborough was the home of Dr. George Rinaldo Southwick and his wife, Mary A. (Leland) Southwick. They previously had lived in an apartment at 31 Massachusetts Avenue. Mary A. Southwick is shown as the owner of 433 Marlborough on the 1912 and 1917 Bromley maps.
George Southwick was a homeopathic physician and gynecologist, and was a professor at Boston University’s School of Medicine. He also maintained his office at 433 Marlborough.
Mary Southwick died in October of 1923. George Southwick continued to live and maintain his office at 433 Marlborough.
The Cambridge Improvement Corporation is shown as the owner of 433 Marlborough on the 1928 and 1938 Bromley maps.
George Southwick died in January of 1930. Shortly before his death, his sister, Annie E. Southwick, came from New York to live with him. After his death, she continued to live at 433 Marlborough until her death in May of 1945.
In 1945, 433 Marlborough was acquired by Hugh Macdonald, who was the assessed owner from 1946.
At about the same time, 433 Marlborough became the home of Rene Marchant and his wife, Alice (Breitel) Arnaud Marchant They previously had lived at 158 St. Botolph. He was a chef and hotel food service manager.
The Marchants leased a portion of the house to Dr. Leo Alexander for his office. He lived in Newton. Leo Alexander was a physician and psychiatrist. He served as chief medical advisor to the American Counsel at the Nuremburg Trials in 1946, and wrote the Nuremburg Code, which established ethical and legal principles relating to medical experimentation with humans. He subsequently was an assistant clinical professor at Tufts Medical School and also served as a consultant to the Boston Police Department, and was credited as being instrumental in solving the Boston strangler case. He continued to maintain his office at 433 Marlborough until the mid-1970s.
In August of 1949, Alice Marchant acquired 433 Marlborough from Hugh Macdonald, acquiring the property as trustee for the benefit of her two sons by her first marriage (to Frank Arnaud): Edouard X. Arnaud and Rene E. Arnaud.
At about the same time, the Marchants separated. Alice Marchant continued to live at 433 Marlborough until her death in November of 1976.
In July of 1977, Peter P. Papesch and his wife, Barbara G. Papesch, as trustees of the 433 Marlborough Street Trust, purchased 433 Marlborough from Edouard and Rene Arnaud. In June of 1977, in anticipation of the purchase, Peter Papesch filed for (and subsequently received) permission to legalize the occupancy of 433 Marlborough as a single-family dwelling and professional office, there being no prior record of the legal occupancy on file with the Building Department.
In February of 1982, Peter Papesch transferred his interest in the assets of the 433 Marlborough Street Trust to Barbara Papesch.
In December of 2005, Barbara Papesch filed for (and subsequently received) permission to convert the property from a single-family dwelling and professional office into a two-family dwelling and professional office.
433 Marlborough remained a two-family dwelling and professional office, assessed as a combined residential and commercial building, in 2014.